Self assembled cationic cell penetrating peptide nanoparticles as efficient cargoes for antimicrobial agents
نویسندگان
چکیده
Background The development of technologies that enable bioactive molecules with low membrane permeability to effectively penetrate biological membranes is one of the greatest challenges in the pharmaceutical field. The HIV-1 transactivating transcriptor (TAT) peptide is one of the most widely used molecular beacons for drug delivery. Cationic antimicrobial peptides have received increasing attention due to their broad spectrum activities and ability to combat multi drug resistant microbes. Our aim is to develop cationic cell penetrating peptide nanoparticles which could efficiently deliver antimicrobial agents against infectious diseases.
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